The Oxbridge Medicine Interview

There’s a lot of myth, intrigue and fear surrounding the interviews at Oxford and Cambridge, and there really needn’t be. Yes, the Oxbridge interviews are different to “normal” interviews, but they’re not the frightening, weird environments that the media likes to portray them as.


The Trick to doing well at Oxbridge interviews

When we all applied, we spent ages trawling the internet, asking our friends, doing anything we could to find the secret to doing well at the interview, but to no avail.

Because unfortunately, there is no trick.

You “just” have to be reasonably intelligent, and be able to think on your feet. You need to know your human biology syllabus inside out, and you need to be able to think out loud and explain your thought process to the interviewers.

If you can do all of that, then you’ll probably get in.


Science-Based Interviews

The primary difference is that Oxbridge interviews are more Science-based than are interviews at other medical schools.

Oxbridge tend to give you maths and science problems to talk through. A lot of times, they’ll ask you a question based on your GCSE or A-level Biology syllabus (something really easy) and then they’ll take that topic and extend it into the realms of first and second year Medicine.

This scares so many people when they think “OMG I haven’t done advanced medical physiology before, wtf do I do??” but in reality, you don’t need any additional knowledge to do well.

What you do need to do is be reasonably intelligent and be able to think through the problem they’re giving you.


Interpreting Graphs

They absolutely love to ask questions about graphs. The graphs can be anything – population graphs, blood glucose graphs, heart monitors, anything.

So it’s very helpful to know what a graph is and how it works.

It’s even more useful to know things like which measure of average you should use for which kind of graph. If you’ve got a perfectly normal distribution then obviously, the mean, median and modes will be identical.

If you’ve got skewed data, the median is probably the better estimate of the average than the mean. That kind of stuff.

You should understand what the slope of a given graph means, and also what the area underneath the graph means. To find out what the slope means, just think about the quantity that y/x represents.

To find out what the area under the graph means, just think about the quantity that y * x represents.

Easy stuff.


Mock Interview Roleplay

Here’s a made-up script that could potentially pass for an Oxbridge interview, to give you some idea of what goes on in them:


Interviewer: What happens to your body physiology when you exercise?

You: Your heart rate increases! Your muscles need more oxygen and therefore, your heart needs to pump faster to supply that oxygen to the muscles. Your muscles also produce more CO2 which the body needs to get rid of, and so the faster rate of the heart means that CO2 can be transported away from the muscle tissue more rapidly.

Interviewer: Very good. Why do your muscles need more oxygen?

You: Oh, because aerobic respiration requires oxygen to make ATP, which is required for cross-bridge cycling in muscle contraction. I believe oxygen acts as the “terminal electron acceptor” in the electron transport chain?

Interviewer: It does indeed! So we’ve established that we need more oxygen, so let’s start thinking about some more mechanisms. You mentioned that your heart rate increases when you exercise – how do you think the heart can know” that you’re exercising?

You: I guess the brain could have something to do with this? So when the brain knows that you’re exercising, it could send a message to the heart via the sympathetic nerves to speed it up?

Interviewer: So let’s think about this in chronological order. Even before you start exercising, something happens in the brain…

You: Oh yeah, the brain can anticipate when you’re about to start exercising. So I guess it makes sense that it would send signals to the sympathetic nerves and cause the heart rate to increase even before exercise starts.

Interviewer: Excellent. Aside from heart rate, there’s something else that happens isn’t there?

You: Oh yeah, heart rate increases but so too does force of contraction. So the overall effect is to increase cardiac output?

Interviewer: That’s exactly right. On a related note, do you know what the formula is for determining arterial blood pressure?

You: Err, can’t say I do I’m afraid. Something to do with force/area maybe? (nervous laugh)

Interviewer: Not to worry. Sort of – the formula I’m talking about is ABP = CO x TPR. Can you think what the abbreviations stand for?

You: Hmm. So ABP must stand for Arterial Blood Pressure and CO presumably stands for Cardiac Output. I know that pressure = force / area, so if the CO is a measure of force, then the TPR term could be inversely proportional to area?

Interviewer: Very astute. TPR in fact stands for Total Peripheral Resistance, and you’re right, the resistance of blood vessels is indeed inversely proportional to their area. Now, when exercising, blood pressure doesn’t change much but cardiac output increases. Forgive the potentially condescending question, but what implications does this have when you consider the formula?

You: Haha, well, we know that ABP is constant and CO increases, so TPR must fall! The total peripheral resistance of the blood vessels must be decreasing.

Interviewer: And how might this happen?

And so on. You probably get the idea.


Helpful Resources

Oxbridge interview crash course